Message SAP XS751 - Message cannot currently be transferred to node & due to connection error

Diagnosis
The message cannot be transferred to node &V1& due to a technical fault.

System Response
The system has flagged this message for a new attempt. The message hasnot yet been sent.
Additional information of the node used (in the system language of thenode):
V4

Procedure
Check the connection from the SAP system to node &V1& with RFCdestination &V2&. Use RFC destination management to check the RFCconnection.
If R/3 is in productive operation, it is advisable to rerouteprovisionally to another node.
You should therefore notify your system administrator.